Treatment of artificial metastases of methylcholanthrene-induced rat sarcomas by autoimmunization of the autochthonous hosts.
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منابع مشابه
Demonstration of host resistance against sarcomas induced by implantation of cellophane films in isologous (syngeneic) recipients.
Whether it is possible to build up host resistance against sarcomas induced by the implantation of cellophane films was studied by pretreating autochthonous and isologous (syngeneic) hosts with heavily irradiated cells of the same tumor. In the ten available autochthonous hosts, whose tumors had been operatively removed, no resist ance could be demonstrated after pretreatment with irradiated ce...
متن کاملDemonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.
by Frehn and Main (13) and by Révész (14) that methylcholanthrene-induced sarcomas, but not spontaneous mammary carcinomas, can induce a state of resistance in isologous mice, i.e., members of the same highly inbred strain in which they have originated. Spontaneous fibrosarcomas in mice did not induce a similar resistance (13). Analogous positive results have been obtained by Baldwin (1) on m...
متن کاملAntitumor activity of lentinan in murine syngeneic and autochthonous hosts and its suppressive effect on 3-methylcholanthrene-induced carcinogenesis.
The antitumor effect of lentinan in syngeneic and autochthonous tumor-host systems and its suppressive effect on 3-methylcholanthrene (MC)-induced carcinogenesis were confirmed using DBA/2 and SWM/Ms hosts. The regressive activity of lentinan against the solid form of Sarcoma 180 was the most effective in DBA/2, SWM/Ms, or A/J mice and less effective in C3H/He or C57BL/6 mice. The growth of a s...
متن کاملLymphoid cell subpopulations infiltrating into autologous rat tumors undergoing rejection.
Lymphoid cell subpopulations infiltrating into autografts of methylcholanthrene-induced sarcomas in rats immunized with autologous tumor cells were identified in terms of immunohistochemical and cytofluorographic techniques using various monoclonal antibodies raised against different classes of rat lymphohemopoietic cells. These antibodies included in this study directed to rat T-cell antigens ...
متن کاملExperimental radiation therapy and apparent radioresistance of autochthonous tumors subcutaneously induced with 3-methylcholanthrene in mice.
The radiation response of autochthonous tumors induced by s.c. injection of 3-methylcholanthrene in ICR/JCL mice was studied. The tumors were mostly fibrosarcomas and grew with an average volume-doubling time of 2.6 days, independently of the time tumor appearance or dose of the chemical used. The tumors were locally and singly irradiated with 6-MV X-rays through a filter. Autochthonous tumors ...
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عنوان ژورنال:
- Cancer research
دوره 28 10 شماره
صفحات -
تاریخ انتشار 1968